By Harry Smith; Royal Society (Great Britain); et al

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Additional resources for The activities of bacterial pathogens in vivo : based on contributions to a Royal Society discussion meeting, London, UK : meeting held on 20-21 October 1999

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S. 1998 Environmental regulation of Salmonella typhi invasion-defective mutants. Infect. Immun. 66, 682-691. Lentner, C. 1981 Units of measurement, body fluids, composition of the body, nutrition. In Geigy scientific tables, Vol. 1. Basle, Switzerland: Ciba Geigy. Lentner, C. 1984 Physical chemistry, composition of the blood, haematology, sonatometric data. In Geigy scientific tables, Vol. 3. Basle, Switzerland: Ciba Geigy. Leuing, K. Y. & Finlay, B. B. 1991 Intracellular replication is essential for virulence of Salmonella typhimurium.

Typhimurium (Heithoff et al. 1997; Conner et al. 1998). However, in infected macrophages DFI and IVET identified two and one gene, respectively, which were not controlled by PhoP/PhoQ (Valdivia & 20 H. Smith Falkow 1997a; Heithoff et al. 1999), thus indicating that this system is not the only one operating. With regard to virulence tests on mutants, a ToxR/ToxS-deficient mutant of V. cholerae produced less colonization and diarrhoea in volunteers than did the wild-type (Herrington et al. 1988), and PhoP/PhoQ-deficient mutants were avirulent for mice (Miller et al.

J. 1989 A two-component regulatory system (phoP/phoQ) controls Salmonella typhimurium virulence. Proc. Natl Acad. Sci. USA 86, 5054-5058. Morgan, A. J. 1985 X-ray microanalysis: electron microscopy for biologists. Oxford University Press. , Hanski, C. & Reichen, E. O. 1991 Expression in vivo of additional plasmid-mediated proteins during intestinal infection with Yersinia enterocolitica serotype 0 8 . J. Med. Microbiol. 35, 257-261. , Liew, F. , Easmon, C. S. F. & Dougan, D. 1988 Characterization of aromatic- and purine-dependent Salmonella typhimurium; attenuated persistence, and ability to induce protective immunity in BALB/c mice.

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