By Gerardo R. Vasta PhD, Hafiz Ahmed PhD

Introduces Groundbreaking methods for Assessing Lectin Function

Lectins and their ligands are below relatively a heavy microscope as a result of their power purposes to pharmacology, immunology, melanoma treatment, and agriculture. With growing to be curiosity within the glycobiology box, the physique of analysis with regards to lectin roles has grown at an explosive price, quite long ago two decades. Animal Lectins: A practical View provides the main up to date research of those carbohydrate-binding, and in all likelihood lifesaving, proteins in a single finished quantity.

This standard-setting source offers new insights into the organic roles of such a lot animal lectins, together with their functionality in an infection prevention via innate immunity. It additionally discusses such lectin behaviors as:

  • Glycoprotein folding
  • Sorting and targeting
  • Cell adhesion
  • Embryogenesis
  • Cell-cell interactions and signaling

Describes the Structural foundation of Protein-Carbohydrate Interactions

Under the editorial suggestions of 2 major protein chemistry specialists and with contributions from well-recognized box gurus, this publication logically and systematically discusses either intracellular and extracellular lectin capabilities. it truly is a vital springboard for destiny box learn and a transparent and concise wisdom base that glycobiology, biochemistry, and immunology researchers can't have the funds for to be without.

Show description

Read or Download Animal Lectins: A Functional View PDF

Similar developmental biology books

Key Experiments In Practical Developmental Biology

Together with many defined by way of the scientists who performed the unique pioneering examine, 27 vintage experiments in developmental biology supply key insights into developmental questions. They identify a bridge among cutting-edge experimental paintings and the laboratory periods taken on the undergraduate and post-graduate degrees.

Developmental Biology (Eighth Edition)

Developmental Biology returns in its ground-breaking re-creation. attempted and validated via 8 earlier versions, Scott F. Gilbert has an uncanny knack of desirable scholar curiosity, beginning minds to the sweetness of developmental biology, while while overlaying all of the required fabric with actual medical rigour.

Indian Herbal Drug Microscopy

Adulteration and misidentification of natural medicinal drugs could cause critical illnesses to shoppers. step one in quality controls of medicinal crops is making sure the authenticity of the specified species for meant use, with anatomical learn enjoying a serious function in settling on and authenticating medicinal crops.

The Oldest Living Things in the World

The Oldest dwelling issues on the planet is an epic trip via time and area. during the last decade, artist Rachel Sussman has researched, labored with biologists, and traveled the realm to photo constantly dwelling organisms which are 2,000 years outdated and older. Spanning from Antarctica to Greenland, the Mojave wasteland to the Australian Outback, the result's a gorgeous and designated visible number of historic organisms not like whatever that has been created within the arts or sciences earlier than, insightfully and accessibly narrated by way of Sussman alongside the best way.

Additional resources for Animal Lectins: A Functional View

Sample text

Biochim. Biophys. Acta. 1572, 209–231. 25. M. 2002 Identification of a fold common to a family of innate immunity recognition factors: Structure of a fucolectin from the European eel (Anguilla anguilla). Nature (Struct. ) 9, 628–634. 26. W. 2004 Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates. Curr. Opin. Struct. Biol. 14, 617–630. 27. W. R. 2006 Characterization of a binary tandem domain F-type lectin from striped bass (Morone saxatilis).

1999). The TC-14 CLD contains an unusual EPS motif in S1, which shows similarities to the motifs of the Man-binding proteins but contains a Ser as a hydrogen-bond donor instead of the Asp in MBP-A. In addition, the crystal structure revealed that this change in specificity is due to a compensatory modification on the opposite side of the ligand-binding site (the S2 WND-motif is changed to LDD), and a 180° rotation of the Gal residue compared with the orientation observed in the Gal-binding MBP-A mutant.

N. 2002 Galectinomics: Finding themes in complexity. Biochim. Biophys. Acta. 1572, 209–231. 25. M. 2002 Identification of a fold common to a family of innate immunity recognition factors: Structure of a fucolectin from the European eel (Anguilla anguilla). Nature (Struct. ) 9, 628–634. 26. W. 2004 Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates. Curr. Opin. Struct. Biol. 14, 617–630. 27. W. R. 2006 Characterization of a binary tandem domain F-type lectin from striped bass (Morone saxatilis).

Download PDF sample

Rated 4.20 of 5 – based on 9 votes