By W. R. Hess (auth.), Yechiel Becker (eds.)

African swine fever (ASF) is brought on by an outbreak that's categorized as a member of the Iridovirinae kinfolk. The affliction within the warthog, the normal host, in Africa was once defined in 1921 via R. E. Montgomery. The reservoir of the vi rus is inti cks. The i ntroduct i on of household pi gs into territory occupied through warthogs i nf ected wi th ASF within the 1960's has endangered the pig all over the world. The family pig is extremely delicate to ASF and develops a devastating disorder that kills the pig with out giving the immune process an opportunity to shield the animal opposed to the virus an infection. the power of ASF virus to contaminate and spoil cells of the reticuloendothelial method leaves a defenseless host that succumbs to infection that could be defined as an received immune deficiency di sease of family pi gs. creation of the virus into Iberia within the 1960's ended in a sequence of ASF epidemics in Spain and Portugal . . and later in France, that prompted heavy monetary losses. among 1976 and 1960, ASF virus made its visual appeal in Malta and Sardinia . . in addition to in Brazil, The Dominican Republic . . Haiti, and later in Cuba. In 1985-6 . . ASF seemed in Belgium and The Netherlands.

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Vifiuela, unpublished data). The possibility that the existence of gene families in ASF virus DNA, a property not described until now for any other virus, is related to the virus escape from the host immune system will have to wait until the function of the putative proteins encoded within those regions is known. The availability of a collection of monoclonal antibodies which recognize ten ASF virus proteins has allowed us to (1) determine the antigenic changes of ASF virus passaged in either porcine macrophages or monkey kidney (VERO) cells, (2) show the existence in a single pig of variants with different antigenic properties and (3) compare the binding properties of 23 field virus isolates (13).

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